Everything you need to know about the four COVID-19 vaccine candidates for children in India | The Weather Channel – Articles de The Weather Channel
As the impact of the second wave of COVID-19 persists, experts have already started to anticipate a potential third wave in India. Whenever it does happen, a certainty this time around would be that more of the population will be vaccinated against the virus, as opposed to the start of the previous wave.
However, this part would not include any children, as only those over the age of 18 have so far been eligible to receive the vaccine. This is a source of concern, and debates about the impact of an impending third wave on children continue to rage.
It is unlikely that the wave will particularly target children, however, with a report published by the Indian Academy of Pediatrics (IAP) last month, stating: “Children are as likely as adults and the elderly to develop infection, but not serious illness. It is highly unlikely that the third wave will primarily or exclusively affect children. “
In addition, a serological survey conducted by the IAP in December 2020 and January 2021 also found that while the percentage of infected children in the 10 to 17 age group was around 25%, as in adults , the prevalence of severe disease in children was indeed lower compared to adults.
Nevertheless, fears surrounding the infection of children prevail, especially given the recent reports of the Delta variant of the coronavirus affecting children in countries like the UK and Singapore
In any case, having children immunized against the virus is of the utmost importance, and the pharmaceutical giants have worked tirelessly to study the effectiveness and safety of vaccines among the young population. For children aged 2 to 18, four vaccines are said to be in preparation in India. Here’s everything you need to know about them:
Covaxin by Bharat Biotech
India’s indigenous vaccine, jointly developed by Bharat Biotech and the Indian Council for Medical Research, is being tested in clinical trials in children aged 2 to 18. The dosage regimen set for children aged 6 to 12 is two, which will be administered at 28-day intervals for the trials. It will be administered intramuscularly, that is, by injection into the muscles.
Trials will take place at 525 centers to assess the safety, reactogenicity and immunogenicity of Covaxin in children. Trials in the age group 2-18 have already started at AIIMS Patna, while AIIMS Delhi is leading the process of recruiting children aged 6-12.
Bharat Biotech nasal vaccine or BBV154
Another candidate for children is the nasal vaccine developed by Bharat Biotech. The vaccine is being hailed as a game changer among the community of experts if all trials are successful.
Called BBV154, it is said to be beneficial in providing mucosal immunity in children, unlike other vaccines. The mucosal immune system plays an essential role in protecting against infections. It specifically protects the sites most prone to viral invasion.
Clinical trials have already started in healthy adult volunteers in India. The vaccine is said to be suitable for both adults and children.
ZyCov-D by Zydus Cadila
Currently being tested on children aged 12 to 18 and adults, ZyCov-D may be the first vaccine to be used for children in India as the company seeks its Emergency Use Clearance (EUA).
The vaccine is being developed by Ahmedabad-based pharmaceutical company Zydus Cadila, which works on DNA-plasmid technology. Scheduled to be India’s second indigenous vaccine, it follows the three dose schedule assigned on day 0, day 28, and day 56.
Covovax from the Serum Institute of India
The vaccine developed by the US company Novavax is in talks to launch clinical trials in children in India by July of this year. The fourth vaccine for children will be manufactured by the Serum Institute of India (SII) in Pune under the name Covovax.
The vaccine has demonstrated an overall efficacy of 90.4% and is based on recombinant nanoparticle technology.
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